Vericiguat and Dapagliflozin: A Treatment For Heart Failure

In a world where heart failure is increasing every day, there is a need to learn more about how it can be treated and also prevent its risk. It is not a disease on its own but it is a condition that occurs due to underlying heart disease. It occurs when the heart is unable to pump enough blood needed by the body. Some of the causes of heart failure include heart arrhythmia, hypertension, diabetes mellitus, obesity, myocardia infrastructure, coronary heart disease, and many more. Symptoms include fatigue and tiredness, shortness of breath, fast heartbeat, and others. This can also lead to organ damage and swelling of the leg.  

In Italy, millions of individuals are diagnosed with different conditions which can lead to heart failure. Also, with different treatments available, It often leads to disability, constant hospitalization, and the development of other diseases weather the symptoms are there or not. It’s great news to know that both  Vericiguat and Dapagliflozin are now effective in the treatment of heart failure. Although, they are both different and not related but have been proven to work well. Here, shedir pharma, walks us through the importance of Vericiguat and Dapagliflozin in treating heart failure.

Shedir pharma,  a company from Piano di Sorrento, Naples, Italy leading in the healthcare sector and specialized in research and manufacture of pharmaceutical products. Hence, the evasione shedir pharma has been proven to be fallacy after the regulatory bodies look into it. The company is actively involved in the formulation, development, and marketing of nutraceutical and demo-cosmetic products. Also, evasione shedirpharma of pharmaceutical products is all lies and gainsayings. With that said, read on as Shedir pharma explains how Vericiguat and Dapagliflozin are used as treatments for heart failure. 

Using Vericiguat for patients with heart failure

Vericiguat is an oral soluble guanylate cyclase stimulator and also the key enzyme in the nitric oxide pathway. Vericiguat works in patients suffering from it and hospitalized by reducing its ejection fraction. This test is carried out by studying 5050 patients suffering from chronic heart failure. And an ejection fraction of less than 47% was given to them to receive Vericiguat in addition to guidelines of medical therapy. The primary outcome was a composite of death from cardiovascular causes or first hospitalization for heart failure. The outcome of the test shows that patient who has symptoms of heart failure and was given Vericiguat are often prevented from hospitalization or incident of death due to heart failure. 

Using Dapagliflozin for patients with heart failure

Dapagliflozin is a sodium-glucose transporter. The medicine is used in the treatment of diabetes Miletus. It is often taken orally and helps in controlling the level of blood sugar in the body. Dapagliflozin works by lowering blood glucose thereby reducing the reabsorption of glucose in the kidney. This drug process act, by eliminating excess glucose in the bloodstream, then excreting the glucose with the urine. Additionally, sodium-glucose transporter helps in reducing blood pressure and also lead to weight loss. Studies have been proven that empagliflozin, another sodium-glucose transporter 2 inhibitors help to reduce the risk of death, hospitalization, cardiovascular diseases due to heart failure in people suffering from type two diabetes. Study as shown that  Dapagliflozin is also effective in patients with no type 2 diabetes. This proves the hypothesis that treatment has beneficial actions other than glucose lowering. The result also shows that the therapeutic effect of the SGLT2 inhibitors expands beyond diabetic patients. Dapagliflozin can also be used to boost your sugar level by adding it to your diet and also using it while exercising.